Assembly as a Programming Language
Let's see assembly as a programming language, and as such there are no mysteries, probable we can even find good tricks purely with regular expressions, bitwise or binary text.
Things like paging, the FPU, etc., are part of the language. They should be seen just like C elements for which we just need to know the structure from a C-like language reference, not look at them as hard tricks to master.
As a low-level language, assembly tells us everything from scratch. Instead of only telling us how to make use of a function, it tells us how to manipulate its lowest level structures in a minimally optimized way.